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At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on four therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.
Join Takeda as a Scientist/ Senior Scientist where you will accelerate drug discovery programs using binding kinetics. You will have strong bench-scientist skills, critical thinking, and analytical skills. As part of the Biologic Analytics and Automation Sciences team, you will report to the Associate Director, Biologic Analytics and Automation Sciences, and work with the Global Biologics team.
- Design and execute diverse sets of binding interaction studies (SPR, BLI, and others) to understand antibody-antigen interactions, ligand-receptor, and enzyme-substrate binding kinetics.
- Develop assays for binding characterization of novel protein targets.
- Process and critically analyze large datasets and interpret results to drive therapeutic antibody selection.
- Identify and prioritize critical experiments to accelerate biologics drug discovery programs with diversifying modalities.
- Constantly assess and implement new technology to the existing workflow to inspire creativity.
- Active engagement with project team members from various cross-functional teams (Global Biologics, Drug Discovery Unit, and Pharmaceutical Sciences).
- Devise and implement both protein analytics and biologics discovery strategies as co-lead for discovery stage programs spanning multiple therapeutic areas including I/O-Oncology, GI/Immunology, CNS, and Rare Diseases.
- Lead developability assessment studies and coordinate Research to Development transition (R2D) of candidates.
- Enable intricate kinetics analysis to support MOA studies, IND filings, external assets evaluations, and therapeutic candidate selection.
- Ph.D. degree in a scientific discipline with 8+ years experience, or MS with 12+ years experience, or BS with 14+ years experience.
- A minimum of 5 years of industry experience in hands-on analytical characterization of biologics is required.
- Project and people management experience is desired.
- Functional area leader with strong expertise in biologics characterization including a deep understanding of binding kinetics using SPR and other orthogonal methods.
- Effective project and resource management skills in a matrix organization.
- Building new capabilities to broaden the scope and capacity of Protein analytics workflow.
- Experience in presenting data and strategy to be presented across the Takeda network involving multiple sites and disease areas.
- Experience in assay development and data analysis.
- A strong publication record is required.
- Comprehensive Healthcare: Medical, Dental, and Vision
- Financial Planning & Stability: 401(k) with company match and Annual Retirement Contribution Plan
- Health & Wellness programs including onsite flu shots and health screenings
- Generous time off for vacation and the option to purchase additional vacation days
- Community Outreach Programs and a company match of charitable contributions
- Family Planning Support
- Flexible Work Paths
- Tuition reimbursement
At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best-in-class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.
Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.
In accordance with the CO Equal Pay Act, Colorado Applicants Are Not Permitted to Apply.
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EEO Statement
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
Boston, MA
Employee
Regular
Full time